Saturday, December 28, 2019

CBG: Precursor To the THC and CBD


This CBG has been considered as the precursor, or the “chemical parent,” of the cannabinoids since all of the other cannabinoids, such as the major CBD cannabinoids and THC, starts as CBG.
The cannabis plants produced cannabigerolic acid or CBGA, a non-acidic form of the CBG. Particular enzymes within the plant then it will break the CBGA down into the other acidic cannabinoids, like the cannabidiolic acid or the CBDA and the tetrahydrocannabinolic acid or the THCA.

Once this cannabis plant is heated or aged, the process is called as decarboxylation, these acids converted to THC and CBD, the active edition of these cannabinoids.


The CBG advantages for glaucoma:

1. Neuroprotective Properties                                   5. Anti-Inflammatory Effects
2. Appetite Stimulant                                                     6. Overactive Bladder
3. Encourage Bone Growth                                          7. Skin Conditions
4. Antitumor Properties                                                8. Antibacterial Properties

Neuroprotective Properties – the CBG that had been illustrated to have the neuroprotective properties, assuring scientists that this cannabinoid alone, or with the combination with the other cannabinoids or the therapies, will be beneficial for this treatment of the neurodegenerative illnesses such as the Huntington’s disease.

Appetite Stimulant – in one animal study of 2016 where they discovered evidence that the CBG may act as the well tolerate appetite stimulants. In the case study, the CBG has been able to elicit the hunger without the need to cause any adverse side effect.

Encourage Bone Growth – the CBG and the other cannabinoids have shown that the interaction with the CB2 receptors stimulates the bone marrow stem cell, recommending they would be advantageous for both of promoting new bone formation and growth and helping the curing of the bone fractures.

Antitumor Properties – in the 2006 laboratory case study found evidence that the array of cannabinoids, with the CBG, has been able to slow down the progression and increase of tumors connected to particular cancers such as breast, prostate, thyroid, leukemia, colorectal, stomach, and glioma cancers and there had been another study in the year 2014 that found the CBG effectively hampered in the growth of the colon cancer.


Anti-Inflammatory Effects – and like with the other cannabinoids, the CBG had been shown to decrease inflammation, prompting researchers that suggest it would be advantageous for the curing of the autoimmune diseases. The CBG has confirmed that it inhibits the cyclooxygenase-2 or COX-2, an enzyme accountable for inducing an inflammatory response.
The anti-inflammatory properties of CBG have also been illustrated to possibly be beneficial for the inflammatory bowel diseases and multiple sclerosis also.

Overactive Bladder – the researchers have discovered evidence that the CBG and the other cannabinoids are efficient for decreasing bladder contractions, recommending that they can be advantageous for curing different bladder dysfunctions.

Skin Conditions – the CBG had been illustrated to possibly inhibit the keratinocyte proliferation, recommending that it would play the therapeutic role in an effort to soothe the skin conditions like the psoriasis.

Antibacterial Properties – the CBG has demonstrated antimicrobial and antifungal properties also. In the 2008 study, the CBG has been highly effective towards the Methicillin-resistant Staphylococcus aureus, or (MRSA), the highly prevalent, yet an antibiotic-resistant strains of bacteria.

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Tuesday, December 17, 2019

What Causes Decarboxylation?


The Decarboxylation process of marijuana takes place when at any rate one of the subsequent two things happens. The partial decarboxylation takes place when a flower normally dries and ages while in the process of curing. Decarboxylation also takes place when the marijuana plants substance is being exposed to heat.


When you are about to leave the marijuana stuff out in an open, in due time the cannabinoid acids will slowly convert to their active shapes just before it will eventually degrade. The drying and the curing of marijuana flowers over time also triggered partial decarboxylation.


Anybody can also force the decarboxylation process by simply heating the cannabis. The marijuana plant material needed to be uncovered to the temperature of about 220 degrees Fahrenheit for around 30 minutes to entirely decarboxylate it. This will permit the cannabinoids in decarb without the need to vaporize them. If you are making edibles, the internal warm of the marijuana-infused baked stuffs likely will not attain the temperature, that is why lots of advises that the flower needed to be decarboxylated just before it is being added to cooked the foods or utilized to create the cannabutter.

Because of the contact with high temperatures, dabbing, smoking, or the vaporizing of marijuana immediately decarboxylates cannabinoids, will make them active during the vapor or smoke, so they
may rapidly go to work the moment they are absorbed by inhalation.

Why is the Decarboxylation Important?

Decarboxylation process is the necessary procedure for using marijuana in tinctures and edibles because it triggers the plant material’s assortment of cannabinoids – with the THC or tetrahydrocannabinol CBD or cannabidiol.

Unheated and fresh marijuana flower do have cannabinoid acids, however, until they are being heated up, these compounds remain in the inactive shape. While there are advantages to consume the raw cannabis and the cannabinoid acids, nutrients, and vitamins, doing so may not cause any kind of psychoactive effect. The juicing of the cannabis leaves and the consuming of raw cannabis buds had been popular among those who are looking to take full advantage of the cannabinoid acids.

In particular, decarboxylation converts the THCA or tetrahydrocannabinolic acid, the non-psychoactive cannabinoid acids to THC, this compound most frequently connected with the marijuana that causes the euphoric high. It converts CBDA or cannabidiolic acid also to the CBD, the sought-after the cannabinoid in the recent years.


These THC and CBD acted as a part of agonists or agonists in the endocannabinoid system cannabinoid receptor – the CB2 and CB1. The endocannabinoid systems are the regulatory network accountable for regulating lots of functions of the body – with pain, sleep, mood, and appetite immune response.


The interaction in between those activated cannabinoids and the cannabinoid receptors differs the discharge of neurotransmitters within the brain, giving up the host of effects. For example, the THC’s psychotropic effects came about due to the activated brain CB1 receptors. That is why for the medical marijuana consumers who depend on the outcomes of the active compounds; this decarboxylation is one crucial step.

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